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Month: March 2021

Hello world!

Posted on: 12 March 2021 Last updated on: 12 March 2021 Written by: admtechna

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PSMA PET-detected mesorectal nodal metastasis: treatment outcomes and clinical implications

World J Urol. 2025 Jun 3;43(1):352. doi: 10.1007/s00345-025-05733-y. ABSTRACT PURPOSE: To evaluate the clinical significance of PSMA-PET/CT-detected mesorectal lymph node metastases in biochemically recurrent prostate cancer patients. METHODS: This is a retrospective analysis of biochemically recurrent prostate cancer patients (post-radical…

Continue reading “PSMA PET-detected mesorectal nodal metastasis: treatment outcomes and clinical implications”…

Convection-enhanced delivery of [177Lu]Lu-labeled gold nanoparticles combined with anti-PD1 checkpoint immunotherapy improves the survival of immunocompetent C57BL/6J mice with orthotopic GL261 murine glioma tumors

Nucl Med Biol. 2025 Jan-Feb;140-141:108970. doi: 10.1016/j.nucmedbio.2024.108970. Epub 2024 Nov 9. ABSTRACT INTRODUCTION: Our objective was to study convection enhanced delivery (CED) of 177Lu-labeled metal chelating polymer (MCP) conjugated to gold nanoparticles ([177Lu]Lu-MCP-AuNP) alone or combined with anti-PD1 immune checkpoint…

Continue reading “Convection-enhanced delivery of [177Lu]Lu-labeled gold nanoparticles combined with anti-PD1 checkpoint immunotherapy improves the survival of immunocompetent C57BL/6J mice with orthotopic GL261 murine glioma tumors”…

18 F-DCFPyL in the Detection of Prostate Cancer Spread to the Lumbosacral Plexus

Clin Nucl Med. 2025 Apr 1;50(4):e232-e233. doi: 10.1097/RLU.0000000000005472. Epub 2024 Dec 13. ABSTRACT In most cases, prostate cancer spreads locally to the seminal vesicles, via lymphatics to pelvic and abdominal lymph nodes, and hematogenously to the bones. Direct invasion along…

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Association of Free-to-Total PSA Ratio and (18)F-DCFPyL Prostate-Specific Membrane Antigen PET/CT Findings in Patients with Biochemical Recurrence After Radical Prostatectomy: A Prospective Single-Center Study

J Nucl Med. 2024 Nov 1;65(11):1731-1739. doi: 10.2967/jnumed.124.267877. ABSTRACT In Canada and across the globe, access to PSMA PET/CT is limited and expensive. For patients with biochemical recurrence (BCR) after treatment for prostate cancer, novel strategies are needed to better…

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Pre-treatment 68 Ga-PSMA-11 PET/CT Prognostic Value in Predicting Response to 177Lu-PSMA-I&T Therapy and Patient Survival

Mol Imaging Biol. 2024 Apr;26(2):360-369. doi: 10.1007/s11307-024-01900-6. Epub 2024 Feb 15. ABSTRACT PURPOSE: To assess the prognostic value of pre-treatment [68Ga]Ga-PSMA-11 PET/CT and other baseline clinical characteristics in predicting prostate cancer (PCa) patients response to [177Lu]Lu-PSMA (PSMA-I&T), as well as…

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